Search results for " UK"

showing 10 items of 72 documents

Genome-wide association meta-analysis for early age-related macular degeneration highlights novel loci and insights for advanced disease

2020

Abstract Background Advanced age-related macular degeneration (AMD) is a leading cause of blindness. While around half of the genetic contribution to advanced AMD has been uncovered, little is known about the genetic architecture of early AMD. Methods To identify genetic factors for early AMD, we conducted a genome-wide association study (GWAS) meta-analysis (14,034 cases, 91,214 controls, 11 sources of data including the International AMD Genomics Consortium, IAMDGC, and UK Biobank, UKBB). We ascertained early AMD via color fundus photographs by manual grading for 10 sources and via an automated machine learning approach for > 170,000 photographs from UKBB. We searched for early AMD loc…

0301 basic medicinegenetic structures610 MedizinGenome-wide association studyMacular Degeneration0302 clinical medicineAdvanced diseaseCD46Genetics (clinical)GeneticsInternational AMD genomics consortium (IAMDGC)ddc:6100303 health sciencesGenome-wide association study (GWAS)3. Good health030220 oncology & carcinogenesisAge-related macular degeneration (AMD)Meta-analysisResearch ArticleGenetic Markerslcsh:Internal medicineUK biobank (UKBB)lcsh:QH426-470Locus (genetics)GenomicsComputational biologyBiologyPolymorphism Single NucleotideGenome-wide association study (GWAS) Meta-analysis Age-related macular degeneration (AMD) Early AMD CD46 TYR International AMD genomics consortium (IAMDGC) UK biobank (UKBB) Machine-learning Automated phenotyping03 medical and health sciencesEarly AMDGeneticsmedicineHumansGenetic Predisposition to DiseaseGenome-wide Association Study (gwas) ; Meta-analysis ; Age-related Macular Degeneration (amd) ; Early Amd ; Cd46 ; Tyr ; International Amd Genomics Consortium (iamdgc) ; Uk Biobank (ukbb) ; Machine-learning ; Automated Phenotypinglcsh:RC31-1245Machine-learning030304 developmental biologyTYRCD46Macular degenerationmedicine.diseaseHuman geneticseye diseasesGenetic architectureMeta-analysislcsh:Genetics030104 developmental biologyGenetic LociCase-Control StudiesAutomated phenotypingHTRA1030221 ophthalmology & optometrysense organsGenome-Wide Association Study
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Neurological diseases and COVID-19: prospective analyses using the UK Biobank

2021

COVID-19 (Coronavirus disease-19) may present with neurological signs, but whether people already affected by neurological conditions are at a higher risk of contracting COVID-19 is still not known. We, therefore, aimed to investigate the association of previously diagnosed neurological conditions with COVID-19. 502,536 community-dwelling UK Biobank participants (54.4% male, mean age 56.6 ± 10.3 years) were included. Among these, 57,463 participants had a diagnosis of neurological conditions (11.43%) and a total of 1326 COVID-19-positive cases were identified (0.26%). Neurological conditions were identified through medical history and linkage to data on hospital admissions (ICD-10 code G00–…

AdultMalemedicine.medical_specialtyUK BiobankNeurologyMovement disordersPopulationLogistic regressionCOVID-19 · Neurological conditions · UK Biobank.Cerebral palsy03 medical and health sciences0302 clinical medicineInternal medicineMedicineHumansMedical history030212 general & internal medicineProspective StudiesProspective cohort studyeducationAgedBiological Specimen Bankseducation.field_of_studybusiness.industryCOVID-19General MedicineOdds ratioMiddle Agedmedicine.diseaseUnited KingdomNeurological conditionsOriginal ArticleFemaleNeurology (clinical)medicine.symptomNervous System Diseasesbusiness030217 neurology & neurosurgery
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„Na Ukrainie za owych dobrych czasów” – „Przed laty. Powieść ukraińska” Paulina Święcickiego

2020

The forgotten work and life of Paulin Święcicki (1841–1876), a writer from Kiev region and active in Galicia, represents a rare, authentic example of Polish‑Ukrainian cultural border. His debut work entitled 'Przed laty. Powieść ukraińska' (1865), despite being an artistic failure, is an interesting link between the heritage of the Romantic 'Ukrainian School' and the historical vision of Polish Borderlands in With fire and sword by Henryk Sienkiewicz. The creation of the 17th‑century reality of Ukrainian grasslands (noble, rural and Cossack existence), battle scenes (fights against the Tatars), romantic‑melodramatic plot – these are all adapted to a unique Ukrainian (not Polish‑centred) per…

BattleContemplationmedia_common.quotation_subjectUkrainianLanguage and LiteratureArt historyPGeneral MedicineArtpowieść historycznaRomanceKozacylanguage.human_languagePaulin Święcicki (Stachurski)Style (visual arts)PortraitlanguagePlot (narrative)szkoła ukraińskaSWORDkresymedia_commonAnnales Universitatis Paedagogicae Cracoviensis. Studia Historicolitteraria
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The Place of Energy Security in the National Security Framework: An Assessment Approach

2022

The term “energy security” is used almost everywhere in economic and political discussions related to energy supply. However, different authors use different meanings to express the concept of energy security. Quite often, this term is used to give more importance or relevance to issues that are often not inherently related to energy security. Attempts to define the essence of the concept of “energy security” have hitherto not been systematic and are characterized by a variety of approaches, and some insufficient justification especially in the aspect of state national security is notable. Our contribution to the discourse development is the consideration of energy s…

ChinaTechnologyControl and OptimizationRenewable Energy Sustainability and the EnvironmentTregression; economic security; energy; Ukraine; correlations; China; U.S.A.Energy Engineering and Power Technologycorrelationseconomic securityregressionElectrical and Electronic EngineeringUkraineEngineering (miscellaneous)energyEnergy (miscellaneous)
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La colonizzazione del Sud-est ucraino: una questione etnica ucraino-russa nella lettura di Dmytro Bahalij

2022

The Ukrainian-Russian ethnic question in Southeastern Ukraine has gained critical importance during the war unleashed by Moscow against Ukraine in February 2022; in this paper I analyze the question of the Ukrainian-Cossack and Muscovy colonization of this very region. I focus on the work by the Ukrainian scholar Dmytro Bahalij (1857-1932), a former member of the Russian Imperial Academy of Sciences. Bahalij emphasizes the key difference between the Ukrainian-Cossack popular colonization of the steppe region and the Moscow administration of these territories. The paper examines some of the main writings by Bahalij and reviews critical articles about his works.

Colonization Ukrainians Cossacks Russians Southeastern Ukraine
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Neurotic generation of Covid-19 in Eastern Europe

2021

This article presents the results of a research survey, which shows the relationship between neuroticism and the coronavirus pandemic, which was performed among students in Poland and Ukraine. The survey was conducted online, on a sample of 1,978 respondents in Poland and 411 in Ukraine. The results indicated that average and high levels of neuroticism were observed among 61% of respondents in Poland and 47% in Ukraine. Regression analysis revealed that the main factors correlated with the level of neuroticism were educational burnout, gender, financial situation, interest in the pandemic, and satisfaction with life. As indicated by the respondents, neuroticism increases with educational bu…

Coronavirus disease 2019 (COVID-19)UkrainianRC435-571Burnouteducational burnout03 medical and health sciencesstress0302 clinical medicinePandemicmental disordersneuroticismOriginal ResearchPsychiatrystudentsCOVID-19Regression analysisPoland and UkraineMental healthNeuroticismlanguage.human_language030227 psychiatryPsychiatry and Mental healthScale (social sciences)languagePsychology030217 neurology & neurosurgeryDemography
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Uno studio sulla “dissenting opinion” con particolare riguardo all’esperienza del diritto inglese

2023

The essay explores the many means through which judicial dissent has traditionally made its way into the English legal system in order to be finally accepted as an ineliminable instrument that the minority has availed itself of to air its differing opinion, mostly in matters of general, public importance. So, the research is in the first place directed towards the identification of the different types of dissent and of the forms (even concurring) in which it may be shaped. Furthermore, the study involves the attempt to find out what reasons may underlie the expression of dissent and whether they may conceal some kind of idyiosincratic state of mind on the part of the dissenters. A view is a…

Dissenting opinion Definition Classifications Admissibility Assenting dissenting and concurring opinion Risks and benefits Famous dissenting opinions in the House of Lords and in the UK Supreme Court Dissenting opinion and progress of the common law
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Humanities and Social Sciences. Latvia: Vol. 27, N 1 (Spring-Summer 2019)

2019

Economic Relations Latvia-USA (1918–1940)gender and leadershipuropean Union’s Futurefemale leadershipBancassurance - Latvia:HUMANITIES and RELIGION [Research Subject Categories]:SOCIAL SCIENCES [Research Subject Categories]democracy and independence - Ukraineeconomic developmentdemocracy and independence - Latvia
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Open collaboration strategy of international retailers: an analysis of co-creator

2017

Nowadays, online channels provide better distribution and communication strategies between companies and consumers. The importance of establishing online tools based on innovations and customer participation, is equally applicable to the international retail sector. Retail companies are able to reach consumers through their online channels, providing better ways to stand out from competitors. The options of joint open collaboration between international retails brands and its consumers implicate a transformation about the traditional communication between customers and companies. The objective of the present work is to analyze how the consumer experience is perceived after its participation…

Fashion industryEngagementCultural comparison UK-SpainCo-creation experienceSatisfactionStructural equation model
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Il nemico è la guerra. Una prospettiva nonviolenta

2022

L'articolo mostra alcune alternative nonviolente concretamente percorribili per fare cessare l'attuale guerra in Ucraina. The paper shows some non-violent alternatives that are practically feasible to end the current war in Ukraine.

Guerra Ucraina NonviolenzaWar Ukraine Nonviolence
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